Stem cell treatment for Cerebral Palsy
Cerebral Palsy is a disorder caused by damage to the brain during pregnancy, delivery or shortly after birth. It is often accompanied by seizures, hearing loss, difficulty speaking, blindness, lack of co-ordination and/or mental retardation. About 25 percent of cases come from a prenatal cause such as anemia, improper nutrition, viruses, x-rays or premature delivery. About 40 percent are caused by a lack of oxygen (hypoxia), and the remaining causes are unknown.
Unlike the currently available conventional treatments, our stem cell therapy is different in the way that we target to repair the brain tissue damage itself and recover functions. Adult stem cell therapy focuses on the root of the problem and not just the symptoms.
Cell death occurs when cells are injured. However, these dead cells are surrounded by damaged and healthy cells. Stem cells have the potential to stimulate the healing of these injured cells by the secretion of cytokines, such as nerve growth factor to promote the body’s self-repair mechanism
The objective of the stem cell treatment is to repair the injured cell area around the lesion. This can lead to improved symptoms mainly in physique and movements.
Like all forms of cerebral palsy, spastic monoplegia results from brain damage. Distinguished from other manifestations of the disease, monoplegia (mono = one) is a movement defect of one of the limbs of the body, generally an arm, on either the right side or the left. It is very rare and many authorities consider it a form of the condition of Hemiplegia with very mild involvement of the other limb on the affected side of the body.
Monoplegia cerebral palsy results from a permanent lesion in the motor cortex area of the brain which may be complete or partial. Like all other types of cerebral palsy, the condition is irreversible meaning that there is no chance of recovery. At best, diagnosis of CP is effectively a process of elimination because there are many other illnesses that are nearly identical to this condition including Erbs palsy, brain tumours, metabolic disorders, brachial plexus palsy, etc.
Stem cells for Monoplegia patients
Cord blood is one source of stem cells that has shown promise in treatments for patients with brain injury. In the preclinical, has shown that cord blood stem cells have the ability to divide and change into neural-like cells. Additionally, these stem cells have been shown to migrate to the area of injury, and to secrete therapeutic factors, which may help repair brain damage. That cord blood stem cells may also alter the body's immune response to injury, by interacting directly with the organs and cells of the immune system that enable the body to better repair itself.
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